Donation after circulatory determination of death (DCDD) is an accepted practice in the United States, but heart procurement under these circumstances has been debated. Although the practice is experiencing a resurgence due to the recently completed trials using ex vivo perfusion systems, interest in thoracoabdominal normothermic regional perfusion (TA-NRP), wherein the organs are reanimated in situ prior to procurement, has raised many ethical questions. We outline practical, ethical, and equity considerations to ensure transplant programs make well-informed decisions about TA-NRP. We (...) present a multidisciplinary analysis of the relevant ethical issues arising from DCDD-NRP heart procurement, including application of the Dead Donor Rule and the Uniform Definition of Death Act, and provide recommendations to facilitate ethical analysis and input from all interested parties. We also recommend informed consent, as distinct from typical “authorization,” for cadaveric organ donation using TA-NRP. (shrink)

"Paradox drives a good deal of philosophy in every tradition. In the Indian and Western traditions, there is a tendency among many philosophers to run from contradiction and paradox. If and when a contradiction appears in a theory, it is regarded as a sure sign that something has gone amiss. This aversion to paradox commits them, knowingly or not, to the view that reality must be consistent. In East Asia, however, philosophers have reacted to paradox differently. Many East Asian philosophers-both (...) in the Daoist and the Buddhist traditions-have openly embraced paradox. They have taken compelling arguments for contradictory positions to suggest that the world is-at least in some respects, and often in very deep respects-inconsistent, and that our best theories of the world will therefore be inconsistent. This book is an initial survey of the writings of some influential East Asian thinkers who were committed to paradox, and for good reason. Their acceptance of contradiction allowed them to develop important insights that evaded those who consider paradox out of bounds"--. (shrink)

Abstract:Subject As Freedom (1930) is correctly regarded as Krishnachandra Bhattacharyya's magnum opus. But this text relies on a set of ideas and develops from a set of concerns that KCB develops more explicitly in essays written both before and after that text, which might be regarded as its intellectual bookends. These ideas are important and fascinating in their own right. They also illuminate KCB's engagement with Kant and with the Vedānta tradition as well as his understanding of freedom itself, including (...) its soteriological dimension. These two essays are "Sankara's Doctrine of Māyā" (1930) and "The Advaita and Its Spiritual Significance" (1936). We explore KCB's conception of philosophy and its relation to spiritual practice through a close reading of these two essays. (shrink)

In this paper I do three things. Firstly, I defend the view that in his most familiar arguments about morality and the theological postulates, the arguments which appeal to the epistemological doctrines of the first Critique, Kant is as much of a fictionalist as anybody not working explicitly with that conceptual apparatus could be: his notion of faith as subjectively and not objectively grounded is precisely what fictionalists are concerned with in their talk of nondoxastic attitudes. Secondly, I reconstruct a (...) logically distinct argument to a fictionalist conclusion which I argue Kant also gives us, this time an argument to the conclusion that it is a good thing if our commitment to the existence of God is nondoxastic. And finally, I argue that this argument is of continuing interest, to Kantians and non-Kantians alike, not only because it raises interesting questions about the relation of morality to belief in God (which go in the opposite direction to most discussions, which focus on whether and to what extent belief in God can be an aid to morality), but also because this ‘Moral Hazard Argument’ seems to be available to religious realists and non-realists alike, thus suggesting that religious fictionalism is not by any means just an interesting version of religious non-realism. (shrink)

Paul Helm’s Faith With Reason articulates and defends an account of reasonable religious faith that claims that religious faith consists of both cognitive and fiduciary elements. One part of religious faith consists of propositions about the object of religious devotion whose strength “ought to conform to the evidence for the proposition in question, ” if they are to held reasonably. Religious belief is not a special species of belief, says Helm, but is subject to the same standards of evidence and (...) criticism as other beliefs. In addition to the epistemic and evidential aspects of religious faith one must add the element of trust. Faith is distinguished from mere notional assent by the fact that the persons of faith actively entrust themselves to God, and depend upon Him to bring about various good purposes they deem to be of great importance. (shrink)

Many philosophers accept that ought implies can (OIC), but it is not obvious that we have a good argument for that principle. I consider one sort of argument for it, which seems to be a development of an Aristotelian idea about practical deliberation and which is endorsed by, amongst others, R. M. Hare and James Griffin. After briefly rehearsing some well-known objections to that sort of argument (which is based on the supposed pointlessness of impossible obligations), I present a further (...) objection, based on a maximally charitable reading of the argument, and conclude that nobody ought to think that it gives them a reason to accept OIC. (shrink)

In this paper, I analyze George Gaylord Simpson's response to the molecularization of evolutionary biology from his unique perspective as a paleontologist. I do so by exploring his views on early attempts to reconstruct phylogenetic relationships among primates using molecular data. Particular attention is paid to Simpson's role in the evolutionary synthesis of the 1930s and 1940s, as well as his concerns about the rise of molecular biology as a powerful discipline and world-view in the 1960s. I argue that Simpson's (...) belief in the supremacy of natural selection as the primary driving force of evolution, as well as his view that biology was a historical science that seeks ultimate causes and highlights contingency, prevented him from acknowledging that the study of molecular evolution was an inherently valuable part of the life sciences. (shrink)

Some ecologists have argued that theoretical model building in population and community ecology has gone evidentially unconstrained. In the essay, I argue that "bottle experiments" offer ecological model building evidential constraints and illustrate this by considering work on chaotic models tested by the dynamics of flour beetles. Critics reply that these experiments are importantly unlike nonmanipulated natural systems and thus do not constitute genuine tests of the models. I conclude by considering two responses to this worry and a suggestion on (...) how to move forward on this debate. (shrink)

Christopher D. Stone has claimed that natural objects can and should have rights. I accept Stone’s premise that the possession of rights is tied to the possession of interests; however, I argue that the concept of a natural object needs a more careful analysis than is given by Stone. Not everything that Stone calls a natural object is an object “naturally.” Some must be taken as artificial rather than as natural. Thistype of object cannot be said to have intrinsic interests (...) and hence cannot be given rights that can protect “its own sake”-which is the sort of right that Stone focuses on. Further, there are other sorts of natural objects which, although they are objects “naturally,” cannot meaningfully be said to have intrinsic interests, and thus cannot have the sorts of rights that Stone is concerned with. Finally, there are other sorts of natural objects which are objects naturally and which have intrinsic interests, but which are not proper candidates for the possession of rights. The prerequisites for being “owed” rights are the possession of intrinsic interests and the capability to suffer when those interests are interfered with or denied or threatened. (shrink)

Discover how the automatic choices you make in life-- without even noticing-- can sabotage you. Fogel and Rosin show you how to learn to interrupt your self-defeating behavior and make better choices.

This paper performs a critical review of twin and adoption studies looking at possible genetic factors in criminal and antisocial behavior. While most modern researchers acknowledge that family studies are unable to separate possible genetic and environmental influences, it is argued here that twin studies are similarly unable to disentangle these influences. The twin method of monozygotic–dizygotic comparison is predicated on the assumption that both types of twins share equal environments, and it is argued here that this assumption is false. (...) Adoption studies have been promoted as a better way of separating genetic and environmental influences. However, there is good reason to believe that adoption studies of criminal and antisocial behavior were confounded by selective placement factors. In addition, these studies suffered from bias and serious methodological errors. In spite of these problems, no adoption researcher claimed to have found evidence of a genetic predisposition for violent crime. It is concluded that the weight of the evidence from family, twin, and adoption studies does not support a genetic basis for any type of criminal or antisocial behavior. The historical background of genetic theories of criminality is also discussed. (shrink)

Race or ethnic identity, despite its imprecise categorization, is a useful means of identifying population differences in mechanisms of disease and treatment effects. Therefore, race and other arbitrary demographic and physiological variables have appropriately served as a helpful guide to clinical management and to clinical trial participation. The African-American Heart Failure Trial was carried out in African-Americans with heart failure because prior data had demonstrated a uniquely favorable effect in this subpopulation of the drug combination in BiDil. The remarkable effect (...) of the drug in reducing mortality in this study has illuminated an important new mechanism of therapy for heart failure. Application of these findings need not be confined to the population studied, but the observation highlights the need for more precise ways to identify individual responsiveness to therapy. (shrink)

After having promoted and then tacitly abandoned the rhetoric of postmodernism, Zygmunt Bauman settled on the metaphor of a modernity that was growing more ‘liquid’ and ‘lighter’ than before. This essay explores the strengths and weaknesses of these metaphors, and attempts to contextualize Bauman’s insights in what has been called by the historian Yuri Slezkine the ‘Mercurian’ culture of diasporic Jewish life.

Among Carl Schmitt's most notable and controversial contributions to political theory was his claim that “all the significant concepts of the modern doctrine of the state are secularized theological concepts.” First formulated in 1922 in his Political Theology, this contention remained constant throughout his long career, as evidenced by its return in his Political Theology II, published in 1970. Here Schmitt's Cadtholic background was clearly apparent, for in so arguing, he was recapitulating the familiar topos of biblical prefiguration in which (...) the New Testament was understood as realizing the latent meaning of the Old. Viewing modern politics as merely the secularized version of a prior theology allowed Schmitt to develop his strong notion of the sovereign as a profane divinity with virtually all of the omnipotent attributes of its alleged sacred predecessor. (shrink)

This paper analyzes a key theoretical assumption of the "classical twin method": the so-called "equal environment assumption" . The purpose of the discussion is to determine whether this assumption, which states that identical and fraternal twins experience similar environments, is valid. Following a brief discussion of the origins of the twin method and the views of its main critics, the arguments of its principal contemporary defenders are examined in detail. This discussion is followed by a critique of several studies which (...) have been cited as evidence in support of the equal environment assumption. It is concluded that the equal environment assumption does not stand up to critical examination, thereby calling into question the claim that the twin method measures genetic effects on human behavior and personality differences. (shrink)

Subtle bodies -- Difference -- Subtle subjects of desire -- "Seering" desire : the between -- Inhabiting sight -- Durée : the aesthetics of desired time -- An ethics of emptiness -- Witnessing : detached immersion -- An ethics of grace : the law of desiring angels -- Conclusion : the angelic ternary.

This paper evaluates the ongoing Finnish Adoptive Family Study of Schizophrenia. The Tienari, Lahti et al. study is the most recent attempt to use adoptees as a way of testing the hypothesis that schizophrenia carries a genetic component, and the purpose here is to present what is probably the first in-depth critical analysis of its findings. The published reports of Tienari and associates are the primary focus of analysis, while problems with other schizophrenia adoption studies using similar research designs are (...) also discussed. Because of factors including the selective placement of adoptees, the low variance explained by the two major hypothesized predictor variables for schizophrenia, the invalidity of the schizophrenia spectrum concept, and the failure to find an index schizophrenia rate greater than general population expectations, it is concluded that the Finnish study cannot be regarded as having produced evidence in favor of the genetic theory of schizophrenia. (shrink)

Human genetics research appears to be approaching a period of re-examination due to the decades-long failure of molecular genetic research to uncover the genes presumed to underlie psychiatric disorders, psychological traits, and some common medical conditions. As currently dominant theories of genetic causation come more into question, we will see a renewed interest in reassessing the potential roles of genes and environment in these areas. To illustrate the potentially harmful and diversionary impact of emphasizing genetics over the environment, the author (...) tells a story in the form of a parable. In this parable, the citizens of a medium-size city are confronted with the task of dealing with a group of arsonists who are systematically burning down several houses each week. The Mayor argues that the best way to prevent arson is to analyze the types of wood used to build the city’s houses, with an accompanying lack of interest in arresting the arsonists. Her opponents argue that regardless of the type of wood used, the city and its citizens should prevent arson attacks by focusing attention on identifying and arresting the arsonists. The Mayor’s position prevails, and the arson attacks continue for years to come at the same time as researchers continue to study and analyze the wood used to construct the houses. Informed readers will recognize the analogous ideas, research strategies, interest groups, publications, and historical controversies related to “nature–nurture” issues, which encompass every aspect of the parable. (shrink)

Trait mindfulness confers emotional benefits and encourages skillful emotion regulation, in part because it helps people more deliberately attend to internal experiences and external surroundings. Such heightened attentional control might help skillfully deploy one’s attention towards certain kinds of stimuli, which may in turn help regulate emotions, but this remains unknown. Testing how trait mindful people deploy attention when regulating their emotions could help uncover the specific mechanisms of mindfulness that confer its emotional benefits. The present study aimed to determine (...) whether high trait mindfulness is associated with sustained attention biases to (i.e. longer gaze at) emotional scenes, when all participants are given the emotion regulation goal of staying in a positive mood. To measure this, we used eye tracking to assess selective attention to positive, neutral, and negative photographs. Higher trait mindfulness was associated with both a stronger attention bias for positive (vs. neutral and vs. negative) images, as well as greater success staying in a positive mood during viewing. Surprisingly, this attention bias towards the positive images did not mediate the relationship between mindfulness and maintenance of positive mood. Future work should compare visual attention to other emotion regulation strategies that may maximise positive affect for mindful people. (shrink)